... My psychiatrist mentioned it might be time to switch me to a different med like Effexor. I was curious if you tapered off the Cymbalta completely, then added a new SNRI; or you simply switched the Cymbalta out for the new med; or if you gradually reduced Cymbalta while gradually adding the new SNRI. I'm currently taking 30mg of Cymbalta (which is making me exhausted), 450 mg of Wellbutrin (making me anxious and sick feeling) and 100mg of Trazadone for insomnia.