I have been taking Zoloft for years and swear by it—at least for depression and self-esteem enhancer. Unfortunately when I increase the dosage to 200mg's, I loose all sex drive and even feelings of intimate emotion, which is very frustrating. The only other antidepressant that I can think worked was Effexor. I am going to discuss with my doctor about decreasing the Zoloft to 100mg and adding Effexor to balance out this side effect.

Does anyone have any comments, suggestion, or tricks that worked or them?