... sertraline to this generic (duloxetine). I'd like to know if there is any Good feedback? Thank you
I took Cymbalta (duloxetine) for many years with great success. Cymbalta affects 2 brain chemicals, serotonin and norepinephrine, while Zoloft (sertraline) only affects serotonin. If the setraline is not working, I suspect this difference in chemistry is why the doctor wishes to try it. We are all different, not one size fits all type thing. Be aware that you'll have to go through the process of weaning off one while starting the other which takes time. Once you have been on a therapuetic dose of Cymbalta it can take upwards of a month to get results. So if you decide to make the change, be patient and give it plenty of time to reach max effectiveness.
I am in my second week of taking duloxetine 20mg and was advised at first just to take it in the morning then see how i got on with it and up the dose to 20mg in the evening which i have done not to bad at the moment and no side affects will keep you posted if you can remind me.
I did not do well on Cymbalta. It can mess with your sleep structure. It did mine so much that the Dr. decided to change me to another antidepressant. He weaned me but I still got the brain zaps that often occur. A close friend had horrible experience with Cymbalta and has since researched it thoroughly. She says it's not a good drug at all, but I have not done all the research she's done. I can only say that it really messed up my sleep and coming off of it was the stuff of nightmares.
I have taken both generic and brand over several decades, though I had to go off Cymbalta and its generic form because of various side effects. I never noticed a difference in the generic or the brand name. I have never heard or read of any difference in the chemical make-up of the two. The generic of a drug is rarely different from the brand name, my doc told me. There are a few exceptions, I understand. My only complaint with Cymbalta has been the horrid withdrawal in which I am going. Tough thing to consider when you have symptoms for which the medication is prescribed.
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