No you don't need to give your body a rest. If you're tired all the time you may need it increased. When you stop it, you have the symptoms back its been helping, and you'll need to start it again, from step one, like when you started it this time and waiting for it to work again. See your dr before you do anything.
I see you mentioned having hypothyroidism. That alone can cause the symptoms you mentioned... right down to the hair loss, fatigue and depression. What are you taking and do you have an endocrinologist?
I hope the peace and calm you are lacking come back to you as your thyroid levels return to normal...
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