I have been taking Effexor XR 37.5 mgs (generic) for just a month. The Effexor really does help me. I had one lite beer w/food & I felt fairly drunk. I have had 2 drinks while on Zolot, Paxil, Celexa, & Prozac & never had a problem. I have tried Wellbutrin but never had any alcohol because I was scared of the seizure risk. Also, on the Wellbutrin bottle label it says to avoid alcohol. The Effexor bottle label says to use caution w/alcohol. Thanks.