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Anyone out there taking Simponi, without Methotrexate?

Responses (3)

suzanne66 28 Jun 2011

I see your question has gone unanswered for some time now. You could try our forum
This link may also be of interest:

Sweet Victory 28 Jun 2011

Thank you for your response. It has been a while. I was weaning off of Methotrexate, and thought I would start to feel pain and swelling again. But I am now off the Methotrexate for 6 weeks, so far, no change in how I feel. The Simponi shot alone is working just fine. I hope it continues.

jisw 24 Nov 2011

Have had RA for more than 7 years and just started simponi, after 6 years on Enbrel. Do not take Methotrexate but take 3 mg of prednisone instead. Am just 2 days after my first simponi injection, but am not happy with the response. Feet are stiffer and more painful than when on Enbrel. How long did it take you to get a response to Simponi??

gmoro0002 30 Jul 2015

It took four weeks for effect that was noticeable overall, but some effect at two weeks. I will tell you after shot 2, the following 14 days I have not taken any Soma nor any Norco. I typically took 2 soma a day and 1/2-1 Norco a day, 2 on really bad ones. I will say at week 7 I am experiencing more relief than on Enbrel which I did great with and honestly didn't think I could do better than. I am taking it for Spondyloarthropathy. free discount card

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