I have Intersitial cystitis
I found amitriptyline really helped me with the pain and still does 18 years later other than the spots where the physical damage to joints is extreme.
I did have trouble with weight gain at first but as long as I don't overindulge it is not a problem now. The thing with amitrip is that it stimulates your appetite in the 2 to 4 hours after taking your dose so you just have to be prepared and have some sensible options on what to eat. Something low calorie but very filling works best. I take mine in the evening so I make sure I eat a light supper then I don't have to worry so much about what I eat later.
Another trick I use is to mix about 2 teaspoons of psyllium seed husks in a glass of water and drink that (if you let it sit for a bit it makes a gel that you can eat with a spoon). It makes your stomach think it is full.
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