I have been to tons of doctors and tried so many medications, patches, creams,acupuncture, massage, tens unit, and more and the pain is getting worse. Unbearable at times. Thank you for any insight you have. Much appreciated.
I have been taking Grapes Seed Extract for 20 yrs soon, I don't deal with DPN but Grape Seed Ex addresses SO MUCH.. A friend deals with idopathic neuropathy and was on Neurontin for like 9 yrs, and once I got her on Grape Seed Ex, she no longer takes the drug... she wanted off the drug anyway. Personally, I believes she has a diabetic issue, but docs say no she tells us... She's a huge sweets eater... PubMed has this info:
""Diabetic peripheral neuropathy (DPN) is one of the most common diabetic chronic complications. The aim of this study was to clarify whether grape seed proanthocyanidins extracts (GSPE) are therapeutic agents against DPN. In this study, we used streptozocin (STZ) to induce diabetic rats. GSPEs (250 mg/kg body weight/d) were administrated to diabetic rats for 24 wk. Motor nerve conductive velocity (MNCV) and mechanical hyperalgesia were determined in the rats. Serum glucose, glycated hemoglobin, advanced glycation end products (AGEs), and tissue malondialdehyde (MDA) and superoxide dismutase (SOD) were determined. Light and electron microscopy were used to observe the changes of nerval ultrastructure.GSPE significantly increased the MNCV, mechanical hyperalgesia and SOD of diabetic rats (p<0.05) and reduced the AGEs and MDA of diabetic rats (p<0.05). After being treated by GSPE, the severe segmental demyelination was decreased and Schwann cells were improved. In conclusion, GSPE plays an important role against DPN. With the decreasing of AGEs and MDA, it can ameliorate oxidation-associated nerval damage. This study may provide a new recognition of natural medicine for the treatment of DPN.""
There is TONS of info on this OPC aka powerful antioxidant. IF one takes a pharma blood thinner, then can't take both of them... Grape Seed Ex works on circulation and cleans the sticky blood.
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