I have been on Lexapro for about a year now. I also have hypothyroidism so when I went to my doctor about a week ago she told me that she has had several patients who have had trouble losing weight and everyone of them were on Lexapro. Has anyone ever heard of this? Also I've been on the contrave for about a week and I feel like I need to decrease the Lexapro because it seems like it's too much with the well butyrin that's in the contrave. is there anyone that is taking the contrave and also on Lexapro? I'm having a really hard time trying to lose weight. I work out four days a week and I have been eating mainly protein and veggies.