I was wondering if anyone can explain a cross taper of antidepressant for me? I know that as you withdraw one you are replacing what's being taken out with the new med. what I don't know is if you are in the middle of the taper and on two different drugs, are you getting a therapeutic effect? Are they doing anything apart from topping up the serotonin the other med was propping up? If each meds work on different receptors does this account for you feeling horrible? How long after a cross taper does the new med go from side effects to benefits? Is it still the standard 4-6weeks before you feel better or quicker since it's not a new start up. Sorry for all the questions but trying to get my head around what's happening during this process.