I am bipolar and recently suffered through 3 weeks of deep depression. Finally, I dragged myself to my psychiatrist and he prescribed Latuda 80 mg. I was instructed to take half a pill for 4 or 5 days and then increase to the full pill. Yesterday was my first full dose day, everything seemed great. I feel better all around. Today however, I took my dose and within an hour or so my tongue was going crazy in my mouth, my jaw was locking and I was drooling. I freaked out, took some ativan and benadryl and then slept for an hour. I woke up and I was fine. Here is the list of meds I take: Depakote ER, Latuda, Ritalin, lorazapam