I never had a problem with inflammation or joint swelling and pain until I started taking Aubagio. I just wondered if anyone else has had these problems. My neurologist even sent me to a rheumatologist thinking I may have RA as well, but those tests came back negative with the results just being inflammation from MS. I was diagnosed in 2004 and was on Avonex for 5 years, then Tysabri, followed by Tecfidera until my lymphocytes got too low. I have been on Aubagio for about 7 months and I just have not felt good (legs ache, joint pain, fatigue).