I'm 32 yrs old, and been on Lamictin(Lamotrigine) (now 250mg/day) for over 5 yrs, for Bipolar 2 and depression. I've had both the headaches & the acne for as long as I've been on the meds, but only recently put 2 and 2 together! (Stupid, I know!) My docs are aware of both the headaches & the acne.