My Wellbutrin is not working like it should. Depression/anxiety still present. Doc suggested Effexor. Would really appreciate feed back about the start up side effects and if it worked or didn't work. How long before it kicked in? I have heard it is hell to get off of. But if it works do not plan on stoping it. Currently on Amitriptyline 12 mg for sleep and Wellbutrin 150 mg SR 1xday. Cannot up the Wellbutrin due to increase in anxiety. Thank you for the any opinion/comments :)