I bought a popular 200mg 90 tabs. What is a good start dose. Got off welbutrin after 8 years and celexa after only 3 months. Started St John Wort but want to stop that. It's realy not doing enough. Looking for something that will relieve my lower back pain along with my depression without the nasty side effects of prescription drugs like being tired and weight gain(celexa). How dI'd Sam-e work for any of you. I have read good things. Seeing my doctor next week. Thanks.