So tomorrow I am to start sertraline. My psychiatrist said to start slow with it. He gave me 50 mg to break in half and take for a week... my question is is it safe to break the 25 mg in half as well and start even slower? I'm a huge baby when it comes to side effects :( but id take 12.5 my for a week then 25 mg for a week then 50mg then I would see him again. Has anyone ever done this? Thanks. Also share experiences if you like. Preferably positive ones.
I started on 12.5mg for a few days & didn’t feel anything at all, I then increased it to 25mg and felt better within 2 weeks. No side effects at all just a bit tired & some restless sleep for a few weeks. Nothing terrible. For most people 25mg isn’t considered a therapeutic dose, I then increased to 37.5mg and was a exhausted zombie. So my pdoc decreased me back down to 25mg. I’d say it’s helped my depression 70%. I’ve tried numerous meds that did absolutely nothing. I’ve been on this dose for 8 months now. For many people the drug gives them energy or at least doesn’t knock them out or the tiredness usually goes away in a few weeks, other side effects usually go away after a few weeks also. I’m not one of those people, I’d increase my dose if I could stay awake! We never know how a med will affect us unfortunately until we try it... best of luck, if you’d feel better trying 1/4 tab for a few days I don’t see any harm in that.
I understand your concern. However, I think your Doctor is right to ask you to start with 25 mg. If it is too much you can always try starting again at 12.5 mg (though it may be difficult to break a 50 mg pill into quarters). Be aware that some people dose as high as 200 mg per day with sertraline and that the starting "therapeutic" dose is considered to be 50 mg. But at the end of the day only you know what you're comfortable with.
Take care for now and all the best.
- Sertraline Information for Consumers
- Sertraline Information for Healthcare Professionals (includes dosage details)
- Side Effects of Sertraline (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Updated 21 Feb 2011 • 2 answers
Updated 8 Oct 2014 • 3 answers
Sertraline - What if your Dr gives you a month to find a psychiatrist to dispense sertraline 100 mg?
Updated 29 Nov 2016 • 4 answers
Updated 12 Jan 2017 • 1 answer
Updated 15 May 2018 • 2 answers