I have to take large doses of opioid medication due to chronic pain. I've been on them for 10 years. I was diagnosed with MDD 30+ years ago. I found that ADs don't seem to offer complete relief now. After familiarization with how the brain & its reward system works (chemically) this now makes sense yet my Psychiatrist keeps prescribing ADs for the MDD. Has anyone found depression/motivation relief while taking opiods and ADs? If yes, can you please let me know what ADs worked for you. Also the details of your pain medications taken at the same time. I'm sorry I ever started this particular treatment for my pain & really am in desperate need for relief from the depression & lack of interest and motivations for anything in life.
I can tell you from my point of view based on personal experience.
We have pharmacists here that can offer technological advice.
I've had MDD off and on for 40 years. I never felt a reall effect from any of the AD.
I cleaned up my personal life (divorce..Lol) and treated myself well to get through those episodes.
I developed an undiagnosed horrific pain syndrome 15 years ago. No Meds because they couldn't diagnose it ;(
8 years ago I developed breast cancer. I'm sure it was from my immune system being lowered from years of pain.
They sent me to the pain center because they wanted my business for the breast cancer . The pain center was a disaster !
They did start me on Oxycodone/OxyContin. 1-1/2 years later I was done with cancer treatment. By now, it took all my energy to get up to the bathroom. No motivation/depressed.
They tried the Cymbalta , Wellbutrin, and something else but none worked.
The only thing that worked for me was Ritalin SA at high doses. I tried Adderall, Strattera and Ritalin LA and felt nothing.
The combo now allows me to WANT to do things in my brain and sometimes I do them.
I agree the lack of motivation is almost as painful as the physical pain.
Good luck to you.
I had MDD for from my early teens well into young adulthood. I tried several ADs myself and most made things worse. Ended up on 6 different anti psychotic meds including AD and AA, plus 2 meds for side effects. All of this paired ok with my chronic pain meds but caused other medical issues. No one thing works the same for 2 different people you just have to keep trying. Sometimes adding an AA to an AD can help. And I wish you the best of luck. Currently I'm on just a maintenance dose of an SSNI as opposed to an SSRI. I found for me it was the better AD to use a SSNI.
Shawnee251; You have a lot of great answers, Which is good it is nice to take and see what has worked for others and use bit;s and piece's from those that have gone through this already It really does help to be able to have a bit of research behind our problems and not have to go through what many of us Have already tried. First, if you have a good doctor that is willing to work with you, I have had chronic pain for so many years it's not even funny. But there were some real good studies on this subject but to cut it short and sweet myself I highly Recommend an antidepressant to help with the pain.
Many get great results from medications such as Amitriptyline as a starter this was one of the Original Medications in the study I was talking about and since then they have found that many with chronic pain seem to do even better on the Snri type Medications I really don't like playing doctor so best to see what your doctor has had good results with, any good pain or primary doctor whoever is managing your pain medication should be more than happy to help you try a few and see what works best for you. Good luck my friend. Give it a go and Remember stuff like this is good to keep in your Journal as time passes we even forget what med's we have tried and this all well help you in the future. Chuck1957 Just remember the most important when you start antidepressants it's not like taking a pain pill many have to build up in your system over a period of weeks to months depending on what your doctor prescribes. Have a great day. CEW.
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Anyone been on Brintellix? My husband has serious depression and has been on several antidepressant?
Posted 4 May 2014 • 4 answers
Posted 15 Sep 2015 • 6 answers
Posted 14 Jun 2016 • 4 answers
Posted 31 Aug 2016 • 5 answers
Posted 13 Dec 2016 • 4 answers