... donts i should follow? like regular liver tests and other health checks which should be peformed..please help somebody..alcohol is destroying me
Antabuse (Disulfiram) is an aid in the management of selected chronic alcohol patients who want to remain in a state of enforced sobriety so that supportive and psychotherapeutic treatment may be applied to best advantage. It is an prescription medication.
Disulfiram is not a cure for alcoholism. When used alone, without proper motivation and supportive therapy, it is unlikely that it will have any substantive effect on the drinking pattern of the chronic alcoholic.
Disulfiram should never be administered until the patient has abstained from alcohol for at least 12 hours.
Initial Dosage Schedule
In the first phase of treatment, a maximum of 500 mg daily is given in a single dose for one to two weeks. Although usually taken in the morning, disulfiram may be taken on retiring by patients who experience a sedative effect. Alternatively, to minimize, or eliminate, the sedative effect, dosage may be adjusted downward.
The average maintenance dose is 250 mg daily (range, 125 to 500 mg), it should not exceed 500 mg daily. Note: Occasionally patients, while seemingly on adequate maintenance doses of disulfiram, report that they are able to drink alcoholic beverages with impunity and without any symptomatology. All appearances to the contrary, such patients must be presumed to be disposing of their tablets in some manner without actually taking them. Until such patients have been observed reliably taking their daily disulfiram tablets (preferably crushed and well mixed with liquid), it cannot be concluded that disulfiram is ineffective.
Duration of Therapy
The daily, uninterrupted administration of disulfiram must be continued until the patient is fully recovered socially and a basis for permanent self-control is established. Depending on the individual patient, maintenance therapy may be required for months or even years.
Trial with Alcohol
During early experience with disulfiram, it was thought advisable for each patient to have at least one supervised alcohol-drug reaction. More recently, the test reaction has been largely abandoned. Furthermore, such a test reaction should never be administered to a patient over 50 years of age. A clear, detailed and convincing description of the reaction is felt to be sufficient in most cases. However, where a test reaction is deemed necessary, the suggested procedure is as follows:
After the first one to two weeks' therapy with 500 mg daily, a drink of 15 mL (½ oz) of 100 proof whiskey, or equivalent, is taken slowly. This test dose of alcoholic beverage may be repeated once only, so that the total dose does not exceed 30 mL (1 oz) of whiskey. Once a reaction develops, no more alcohol should be consumed. Such tests should be carried out only when the patient is hospitalized, or comparable supervision and facilities, including oxygen, are available.
Management of Disulfiram-Alcohol Reaction
In severe reactions, whether caused by an excessive test dose or by the patient's unsupervised ingestion of alcohol, supportive measures to restore blood pressure and treat shock should be instituted. Other recommendations include: oxygen, carbogen (95% oxygen and 5% carbon dioxide), vitamin C intravenously in massive doses (1 g) and ephedrine sulfate. Antihistamines have also been used intravenously. Potassium levels should be monitored, particularly in patients on digitalis, since hypokalemia has been reported.
Please do check with a doc/pharmacist for more detailed info, take care, & please do not self medicate.
Well done in admitting that alcohol is destroying you and wanting to do something positive about.
Antabuse is a kick starter but I don't recommend self medication - just consider the point where the self administering/ministering of alcohol has taken you. I myself am a recovering alcoholic and know where you are at but there is hope... I suggest you speak to your doctor, you need support at a time like this and also something to help with alcohol withdrawals.
Next I suggest, but its entirely up to you you seek out a support group either online or by contacting your local Alcoholics Anonymous group. I suggest you at least go see how it might work for you, there is no obligation for you to return. I am a member but not evangelical about it, personally it has been the only thing thats worked in keeping me stopped. I could, at times, stop but the problem was staying stopped. Boy is my life a whole lot simpler and chaotic and most of all free of fear since I stopped.
I wish you great encouragement and please feel free to contact me if you need any support, at any time.
- Antabuse Information for Consumers
- Antabuse Information for Healthcare Professionals (includes dosage details)
- Side Effects of Antabuse (detailed)
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