I tapered myself of Zoloft (sertraline) 50 mg I had been taking for over 5 years and have been completely off it for 2 weeks now. I am having severe anger issues. I get super angry and stay that way, seething inside all day long. I feel like the reasons I get angry are legitimate--to be irritated, not furious. I am able to curb most of the outward signs but it is getting harder. Does anyone know how long it takes for this to go away or is this a sign that I am going to have to use this drug for life? I just feel like I want to have a change to live life without the fog of an antidepressant (although they didn't cause bad side effects, just minimal ones, lower sex drive, lack of ambition (still do what has to be done but never get around to extras) and maybe a little bit of memory issues. I have searched and searched but not found a true answer. Has anyone had this and what did you do?