Have taken Zoloft for a year. I also have IBS, and chronic pain. Dr. switch to amitripyline 75mg daily and vortioxetine 10 mg daily. I also want to know what time of day would be best? A lot of reviews said taken at night.
The amitriptyline you definately want to take at night. Its going to make groggy. When you're taking 2 antidepressants there is a risk of a rare reaction called serotonin syndrome, but many of us are on 2 and have no problem you just have to be aware of that. The vortioxetine should be taken in the am.
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