I am currently take 60mg of Amitriptylene for Fibromyalgia, and started Mirtazipine for depression last week. Since starting the Mirtazapine I have noticed my pain is increasing.
Hi, paws! Mirtazapine shouldn't cause your amitriptyline not to work, but the combination itself can increase the risk of serotonin syndrome. This condition is very rare, but very serious and if while taking the combination you notice any new or unusual symptoms or an increase in your previous symptoms you should notify your physician immediately.
Best wishes, WCV
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Posted 12 Jan 2010 • 2 answers
Posted 23 Jun 2013 • 2 answers
Amitriptyline - Does Amitriptylene at 125mg taken at night for 20 years lose it's efficacy or, have?
Posted 28 Dec 2014 • 2 answers
Posted 27 Sep 2015 • 3 answers
Posted 2 Apr 2018 • 4 answers