I take amitriptyline for migraines 10 mg once a night I also have sciatica and have been beaten... down lately from sciatica ... my doc prescribed me flexeril told me to not take the amitriptyline tonight and to take the flexeril every night for ten days also 10 mg along with anti inflammatory ... is this safe? im reading we need to ween off off the amitriptyline and not just suddenly stop .. and that there is more importantly a MAJOR interaction between the two drugs ... i just took my amitriptyline last night ... am i safe to switch it to flexeril in a 24 hour period? i have taken amitriptyline for about a yr