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How long does it take to get amitripiline out of your system?

Responses (1)

suzanne66 5 May 2013

It takes around 5.5 x elimination half life's for a drug to be cleared from your system.

Amitriptyline is over 90% protein bound. Its elimination half-life varies from 10 to 50 hours, with an average of 15 hours.

If we use the maximum elimination half life of 50 hours it'll take 275 hours i.e. 11.45 days (5.5 x 50 hours).

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