I am prescribed to take 2 24mg a day and I take them at night that works for me, with results every morning! but my question is I take prescribed pain pills is there a way that this medicine flush my pain pain pills out everyday? Every morning when I go its no strain just like urinating, it's like water and I feel great! before amitiza I couldn't go for weeks at a time and when I did it was terrible constipation and stamach pains! But is it possible for this medicine to be flushing my system out?