After being on a pill taken every 4-6 hours for chronic back pain. My PS has started me on 5mcghour patches to be changed every 7 days. I was wondering what is the quickest I can expect to get relief, and if when applying the patch for the first time is there one application site better than another for the first patch being this is the one we need to work the quickest. Right? And also are there any tips on ways to lessen the irrigation of the adhesive on the patch when applying it to the skin? Thank you, all helping comments are greatly appreciated.