Just because you are tolerant to one medication doesnt mean you are tolerant to another. For example, a person may be quite tolerant to say, oxycodone and perhaps on a high dose. Her Dr may try her on morphine which she may not have as much tolerance to and be able to get the same pain control on a smaller equivalent dose. It worked for me. I switched from Oxycontin to MSContin and I am able to take a lower dose equivalent of the morphine.
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