.. I started duloxetine a month and a half ago. No side effects at all. Some headache but nothing else. I started on 30mg, after 60, 90, and now for 10 days I'm on 120mg with no side effects. I have seen a bit of improvement..for my mood but very little. I'm still have bad thoughts ..I'm so frustrated after reading other people stories being on this drug for 2 weeks or a month and are back to normal. Why it's not working for me even on 120mg without side effects. I am completely disconnected same as before starting duloxetine.. Any advice please? Should I be hopeful that sth will turn for good? Just be honest..