I was taking 10mg of Lexapro for 2 years for panic attacks. It helped and I did not have any panic attacks while on Lex. But I gained 25 pounds and could not lose weight no matter what diet I tried. I have switched to Effexor after learning that it does not cause weight gain, but rather helps in weight loss. The doctor said I did not have to wean off of Lex. I have been on Effexor for 2 months now and am now beginning to experience the withdrawals from Lex: brain zaps, dizziness, pain in my shoulder and right arm (feels like arthritis), eye sensitivity to bright light, sleepy during the day, sleepless at night. I have been taking melotonin to help me sleep. I haven't loss any weight yet. I would really like to get off of the meds but am afraid I will start getting the panic attacks again. I am currently going through menopause and having irregular menstral cycles. Has anyone made the connection of menopause with panic attacks? I am taking multi-vit, B-12, Omega 3, vit C, cranberry, Benicar for high blood pressure. If I were to wean off of meds (not vitamins) will the panic attacks come back? I am hoping the Effexor will solve the problem for the panic attacks and help me to lose the weight I gained and then maintain. Answers, comments, suggestions are greatly appreciated!