I have been on Zoloft for over 10 years now after my depression began when my mother passed away and on klonopin. Having very difficult time now. My doctor has tried adding seroquel which made me anxious then tried me on a similar med and same reaction. Now I have been given Wellbutrin 150mg to add to my Zoloft of 100mg. I also take for sleep trazadone for the last 5-6 years as I have insomniaand nightmares after my sister passed away. Does anyone know how this has worked for them or any input?