I take 20 mg adderall in morning and 10 mg adderall in the afternoon. I also take 1 mg tenex and 10 mg lexapro at night. Usually I need 0.5 mg of ativan to sleep-does anyone know if this combo is safe or effective. I have ADD and depression, I am 49 year old female.
It seems that lexapro isn't too compatible with adderall. Here's what I found:
amphetamine ↔ escitalopram
Applies to: Adderall (amphetamine/dextroamphetamine), Lexapro (escitalopram)
GENERALLY AVOID: Several case reports suggest that serotonin reuptake inhibitors may potentiate the pharmacologic response to sympathomimetic agents. The exact mechanism of interaction is unclear. In one case report, a patient experienced jitteriness, racing thoughts, stomach cramps, dry eyes, palpitations, tremors, and restlessness following a single dose of phentermine ingested approximately a week after she had discontinued fluoxetine. Because of the long half-life of fluoxetine and its metabolite, an interaction with fluoxetine is possible. Similar toxic reactions have been reported when fluoxetine was used concomitantly with amphetamine or phenylpropanolamine.
Additionally, some sympathomimetic agents such as amphetamines may possess serotonergic activity and should generally not be administered with serotonin reuptake inhibitors because of the additive risk of serotonin syndrome, which is a rare but serious and potentially fatal condition thought to result from hyperstimulation of brainstem 5-HT1A and 2A receptors. The interaction was suspected in a patient treated with dexamphetamine who developed symptoms consistent with the serotonin syndrome approximately 2 weeks after the addition of venlafaxine. The medications were discontinued and the patient was given cyproheptadine for suspected serotonin syndrome, whereupon symptoms promptly resolved. A second episode occurred when dexamphetamine was subsequently resumed and citalopram added. The patient improved following cessation of citalopram on his own, and residual symptoms were successfully treated with cyproheptadine.
Not to snipe or anything, but as you know, drug companies are required to report even one adverse reaction. I'm concerned that there might be more than one physician prescribing and are unaware of other meds. I always carry a card with all meds to every doc appt to make sure that the right hand knows what the left is doing.
Just my 5 cents worth,
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Posted 29 Oct 2011 • 1 answer
Posted 29 Jun 2012 • 3 answers
Posted 15 Apr 2014 • 1 answer
Posted 18 Feb 2017 • 2 answers
Posted 9 Jun 2018 • 0 answers