I talked to my DR. and he said taking adderall Monday-Friday but not on the weekend or not taking it only 1 day a week is harder on the body than if I took a different medication, like nuvigil, but I like how I am on adderall. I take adderall everyday I work, and I don't when I don't work. But, my schedule changes weekly because I work in a distribution center so I can either work 5 days a week and get 2 days off. Or I can work 2 weeks or more straight with out getting a day off at all.