my dermatologist perscribed me epiduo and then gave me aczone as well... but one of the side affects of aczone is- when used with benzoil peroxide (wich is in epiduo) this may turn face orange or yellow... does this really happen?
Interactions between your selected drugs
benzoyl peroxide ↔ dapsone
Applies to: Epiduo (adapalene/benzoyl peroxide topical), Aczone (dapsone topical)
In one clinical study, topical application of dapsone followed by benzoyl peroxide in subjects with acne vulgaris was associated with a temporary local yellow or orange discoloration of the skin and facial hair in 7 out of 95 subjects, with resolution in 4 to 57 days. The mechanism of interaction is unknown.
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