Sertraline (Zoloft) has been approved by the U.S. Food and Drug Administration for treatment of premenstrual dysphoric disorder (PDD). Sertraline is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Sertraline affects chemicals in the brain that may become unbalanced and cause depression, panic, anxiety, or obsessive-compulsive and PDD symptoms.
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