It is contra indicated for use with alcohol as alcohol makes it undergo a chemical change to a longer lasting other drug as far as I can tell: https://www.drugs.com/pro/acitretin-capsules.html It is a huge document and the drug interactions (of which there are many), but you will find the contra indications/adverse reactions about one third down. Most of it is devoted to birth defects, not just the chance of them but the almost certainty of having a badly deformed child if it lives.
Clinical evidence has shown that etretinate can be formed with concurrent ingestion of acitretin and ethanol (see boxed CONTRAINDICATIONS AND WARNINGS and CLINICAL PHARMACOLOGY: Pharmacokinetics)."
Please take care as there is also a warning about increased photosensitivity.
- Acitretin Information for Consumers
- Acitretin Information for Healthcare Professionals (includes dosage details)
- Side Effects of Acitretin (detailed)
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