I have been on 150 mg Bupropion (Welbutrin) mornings for depression for 3 years but have had horrible nightmares daily. Originally on Prozac and other antidepressants, this med has worked best with the least side effects, except for this sleeping problem. Often these dreams are so bad that I cannot return to sleep and I get only a few hours rest. By accident, I discovered taking 800 mg of ibuprofen (with food) in the evenings it allowed for a long restful sleep without the nightmares. I took the ibuprofen originally for some muscular aches and pains I experienced one day after working in the yard. I have been taking it since and find no more nightmares occur. My doctor cannot explain it but suggests that I never take the bupropion and ibuprofen within 8 hours of each other due to side effects. I also take a small aspirin for cardiac prevention and he told me to keep the same distance from the ibuprofen as it could minimize the positive effects of the aspirin.Has anyone else suffering from nightmares on this drug tried this common Bupropion side effect cure?