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Can I take two 50 mg of tramadol at 10:58 and a 1 mg of larzpanif I have a kidney deise?

Responses (1)

Inactive 18 Dec 2012

Hello bpatterson419,

Tramadol (Includes Tramadol) ↔ Renal Dysfunction
Severe Potential Hazard, High plausibility
Applies to: Renal Dysfunction
Tramadol and its metabolites, one of which (referred to as M1) is pharmacologically active and a more potent analgesic than tramadol itself, are primarily excreted in the urine. The rate and extent of excretion of both tramadol and M1 have been shown to decrease in patients with impaired renal function. Therapy with tramadol should be administered cautiously in such patients. The manufacturer recommends increasing the dosing interval to every 12 hours, with a maximum daily dosage of 200 mg, in patients with creatinine clearance below 30 mL/min.

I suggest you discuss this interaction with your Dr.

Take care,


kaismama 18 Dec 2012

Good morning sunshine. You stuck on that second one too? lol

Inactive 18 Dec 2012

Morning my friend. free discount card

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