I have tried several drugs for Fibromyalgia, but they either didn't effect the pain and stiffness or contained an anti-depressent. I suffered side effects that caused me to discontinue use. Pain pills (Norco, etc) doesn't seem to have an effect on the pain either. Would 5-hydroxytryptophan be a prospect for me to try? I also suffer from rheumatoid arthritis, deteriating spine and hip, and periphreal neuropathy. But out of all of my disorders Fibromyalgia has impacted my quality of life the most. I also suffer from chronic fatigue and has insomnia.