I'm 42 was on the depo shot from 1994 to June 2017 my last actual shot was April 2017 I still haven't had a period I do have all the signs of early menopause but didn't know if the depo shot or early menopause or both could cause meI'm 42 was on the depo shot from 1994 to June 2017 my last actual shot was April 2017 I still haven't had a period I do have all the signs of early menopause but didn't know if the depo shot or early menopause or both could cause me not to have a period yet since I was on it for so many years I'm not sure if the depo has caused this or not I know or have been told in the past that the length of time I had been getting it wasn't good for my body my last period was before I had my son over 23 years ago not to have a period yet since I was on it for so many years I'm not sure if the depo has caused this or not I know or have been told in the past that the length of time I had been getting it wasn't good for my body my last period was before I had my son over 23 years ago