I've been suffering depression and anxiety for 14 yrs and it's mostly stayed under control but last Feb I ended up with a hospital admission. Since then I've had my lithium increased to 800mg from 600mg and also had a my anti depressant changed from Lexapro 20mg to Brintellix 15mg. Unfortunately I've had very little improvement with both the depression and anxiety and it's coming to a point where I'm just fed up with everything. How much longer should I have to put up with feeling like this,my psychiatrist just keeps saying give it a chance (I've only been on 15mg of Brintellix since Dec 17). I'm not living anymore just existing. My next appointment is wed coming? I'm also on valdoxan 50mg, Phenergan 25mg and Valium 2mg 3 times daily.