... first period after the baby . I was taken off xarelto for a day n then put on the depo shot (hormone therapy ) to help me clot and stop the bleeding and to keep me from having periods so i wouldnt hemmorage again and had to start xarelto again that same day . Well two months after i went for a walk and started bleeding again but not as bad and i have been bleeding for a month now . . Is it safe to be on the depo shot while on xarelto ?or is it whats causing me to bleed ? I have an appointment for my second dose of the depo shot tomorrow and im afraid its goin to make me bleed more ... pls answer asap as i am debating whether or not to get the shot or not