... there anything I can do to prevent the itching? (I've already tried benedryl spray on the application site but it didn't help.) I had been using the patch for 3 yrs with no side effects however recently the severe itching started so I wondered if the adhesive had changed; my MD said no, it's the same as always. Could my body have become allergic to the patch after years of use? Is there a way to prevent the severity of the itching (it wakes me up from an otherwise sound sleep). I would so appreciate some help!!!