I checked out an eqivalency chart that puts oral hydromorphone at 4 times the potency (mg for mg) of oral morphine sulphate. 180 mg of morphine sulphate is the equivalent of 45 mg hydromorphone. Other calculators use a ratio of 5 to 1 which would put you at 36 mg of hydromorphone
Note, the same first calculator has this to say: "Tips and Warnings When Converting TO this Opioid
Extreme caution should be exercised when replacing morphine with hydromorphone. Hydormorphone is considerably more potent than morphine (10 mg injectable morphine = 1.5 mg hydromorphone), which has been fatal because of miscalculation and/or decimal point errors."
Hopefully expert member Masso has something to add.
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