I've been taking glucophage for almost a year now. The first 8 months aprox it worked great, my A1C went to regular levels and I lost some weight. I stopped taking glucophage for a little over a month because I went on a business trip and simply forgot to get a refill. Ever since I got back I've started taking it again but I've started gaining weight and my A1C is worse. I've been taking it for 4 months now, I'm exercising regularly, my diet is the same as it was during the first 8 months, but I keep gaining weight. Have I developed some sort of resistance to it? Should I do something else?
Definitely talk to your doctor. You're doing all the right things and it's excellent that you're keeping such a good watch on both your health and your A1C numbers. I don't personally believe that being off of it for a month would make you tolerant to it or anything like that, if anything I would believe that it would make you increase your sensitivity to it, but there are other medications that you can try in lieu of Metformin, and based on the fact that it's no longer working for you, that may be an order for you to try this for your health based on your doctors advice. Four months is a long time to try to get back on track so it's definitely worthwhile to try to get your blood test done and also ask for a fasting insulin test which will check to see how insulin resistant you are. Unless you are a full-blown diabetic, this will be a good measure of how hard your pancreas is having to work to keep up with the food you're putting into your body and the amount of energy your cells are converting (I.e. Glucose). If you are insulin resistant, no matter how hard your pancreas works the food you eat is not going to be converted into energy and your pancreas is going to work harder and harder to push out additional insulin because it's essentially being "ignored" by the cells of the body. It's not part of your regular blood panel but it is just one extra little test that they can include as part of your normal blood panel.
- Glucophage Information for Consumers
- Glucophage Information for Healthcare Professionals (includes dosage details)
- Side Effects of Glucophage (detailed)
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