Husband given 1 Oxy prior to knee replacement. Fine until OR then throwing up, sweaty, clammy, irregular heartbeat and Cardiologist called in. ECG was done and showed blip. Stabilized and went to ICU. 3 more ECG's done in 24 hour period but showed normal. Stress test 3 weeks ago showed problem. Followed with ECG. Diagnoses: ST Depression and enlarged heart. Only getting 43% oxygen. Cardiologist said Oxycontin didn't do it, but that is the only time he has experienced effects like that. Codeine allergy.