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Generic Name: drospirenone and ethinyl estradiol (dro SPY re nown, ETH in il, ESS tra dy ol)
Brand Names: Gianvi, Loryna, Nikki, Ocella, Syeda, Vestura, Yasmin, Yaz, Zarah

What is Yaz?

Yaz (drospirenone and ethinyl estradiol) prevents ovulation (the release of an egg from an ovary) and also cause changes in your cervical and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Yaz is used as contraception to prevent pregnancy. It is also used to treat moderate acne in women who are at least 14 years old and have started having menstrual periods, and who wish to use birth control pills to prevent pregnancy.

Yaz is also used to treat the symptoms of premenstrual dysphoric disorder (PMDD), such as anxiety, depression, irritability, trouble concentrating, lack of energy, sleep or appetite changes, breast tenderness, joint or muscle pain, headache, and weight gain.

Important information

Do not use Yaz if you are pregnant or if you have recently had a baby.

You should not take Yaz if you have any of the following conditions: uncontrolled high blood pressure, heart disease, a blood-clotting disorder, circulation problems, diabetic problems with your eyes or kidneys, unusual vaginal bleeding, liver disease or liver cancer, severe migraine headaches, if you smoke and are over 35, or if you have ever had breast or uterine cancer, jaundice caused by birth control pills, a heart attack, a stroke, or a blood clot.

You should not take Yaz if you smoke and are older than 35 years of age. Smoking can increase your risk of blood clot, stroke, or heart attack while taking Yaz.

You may need to use back up birth control, such as condoms or a spermicide, when you first start using Yaz or if you miss a dose. Follow your doctor's instructions.

Some drugs can make Yaz less effective in preventing pregnancy, including antibiotics, hepatitis C medications, HIV/AIDS medications, seizure medications, or barbiturate sedatives. Tell your doctor about all other medications you use.

Before taking this medicine

Smoking can increase your risk of blood clots, stroke, or heart attack while taking Yaz, especially if you are older than 35 years of age. Your risk increases the more you smoke. You should not take combination birth control pills such as Yaz if you smoke and are older than 35 years of age.

Do not use if you are pregnant. Tell your doctor right away if you become pregnant, or if you miss two menstrual periods in a row. If you have recently had a baby, wait at least 4 weeks before taking Yaz.

You should not take Yaz if you have:

  • untreated or uncontrolled high blood pressure;

  • heart disease (coronary artery disease, uncontrolled heart valve disorder, history of heart attack, stroke, or blood clot);

  • a blood-clotting disorder or circulation problems;

  • problems with your eyes, kidneys or circulation caused by diabetes;

  • a history of hormone-related cancer such as breast or uterine cancer;

  • unusual vaginal bleeding that has not been checked by a doctor;

  • liver disease or liver cancer;

  • a history of jaundice caused by pregnancy or birth control pills; or

  • severe migraine headaches (with aura, numbness, weakness, or vision changes), especially if you are older than 35.

To make sure Yaz are safe for you, tell your doctor if you have:

  • high blood pressure, varicose veins;

  • high cholesterol or triglycerides, or if you are overweight;

  • an electrolyte imbalance (such as high levels of potassium in your blood);

  • a history of depression;

  • underactive thyroid;

  • gallbladder disease;

  • diabetes;

  • seizures or epilepsy;

  • a history of irregular menstrual cycles;

  • tuberculosis; or

  • a history of fibrocystic breast disease, lumps, nodules, or an abnormal mammogram.

The hormones in Yaz can pass into breast milk and may harm a nursing baby. Yaz may also slow breast milk production. Do not use if you are breast feeding.

How should I take Yaz?

Take Yaz exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take Yaz in larger or smaller amounts or for longer than recommended. You will take your first pill on the first day of your period or on the first Sunday after your period begins. You may need to use back-up birth control, such as condoms or a spermicide, when you first start using this medicine. Follow your doctor's instructions.

The correct way to take Yaz is to take one pill every day at the same time in the order directed on the package. Preferably, take the pill after the evening meal or at bedtime, with some liquid, as needed. Yaz can be taken without regard to meals.

When the Yaz pill pack runs out, start a new pack the following day. You may get pregnant if you do not take one pill daily. Get your prescription refilled before you run out of pills completely.

The Yaz-pill pack has 24 light pink pills (with hormones) to be taken for 24 days, followed by 4 white pills (without hormones) to be taken for the next four days.

You may have breakthrough bleeding, especially during the first 3 months. Tell your doctor if this bleeding continues or is very heavy.

Use a back-up birth control if you are sick with severe vomiting or diarrhea.

If you need surgery or medical tests or if you will be on bed rest, you may need to stop using Yaz for a short time. Any doctor or surgeon who treats you should know that you are using birth control pills.

While taking Yaz, you will need to visit your doctor regularly.

Store this medicine at room temperature away from moisture and heat.

What happens if I miss a dose?

Follow the patient instructions provided with Yaz. Ask your doctor or pharmacist if you do not understand these instructions. Missing a pill increases your risk of becoming pregnant.

If you miss one active pill, take two pills on the day that you remember. Then take one pill per day for the rest of the pack.

If you miss two active pills in a row in Week 1 or 2, take two pills per day for two days in a row. Then take one pill per day for the rest of the pack. Use back-up birth control for at least 7 days following the missed pills.

If you miss two active pills in a row in Week 3, throw out the rest of the pack and start a new pack the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack that day.

If you miss three active pills in a row in Week 1, 2, or 3, throw out the rest of the pack and start a new pack on the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack that day.

If you miss two or more pills, you may not have a period during the month. If you miss a period for two months in a row, call your doctor because you might be pregnant.

If you miss a reminder pill, throw it away and keep taking one reminder pill per day until the pack is empty. You do not need back-up birth control if you miss a reminder pill.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, and vaginal bleeding.

What should I avoid while taking Yaz?

Do not smoke while taking Yaz, especially if you are older than 35 years of age.

Yaz will not protect you from sexually transmitted diseases--including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.

Yaz side effects

Get emergency medical help if you have signs of an allergic reaction to Yaz: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using birth control pills and call your doctor at once if you have:

  • sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;

  • sudden cough, wheezing, rapid breathing, coughing up blood;

  • pain, swelling, warmth, or redness in one or both legs;

  • chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea, sweating, general ill feeling;

  • a change in the pattern or severity of migraine headaches;

  • nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

  • swelling in your hands, ankles, or feet;

  • a breast lump; or

  • symptoms of depression (sleep problems, weakness, tired feeling, mood changes).

Common Yaz side effects may include:

  • nausea, vomiting;

  • acne;

  • breast tenderness;

  • headache, mood changes, feeling tired or irritable;

  • weight gain; or

  • changes in your menstrual periods, decreased sex drive.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Yaz?

Some drugs can make Yaz less effective, which may result in pregnancy. Other drugs may interact with this medicine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about Yaz.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Yaz only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2016 Cerner Multum, Inc. Version: 7.01. Revision Date: 2015-08-06, 11:43:10 AM.

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