Terramycin Ophthalmic OintmentThis page contains information on Terramycin Ophthalmic Ointment for veterinary use.
The information provided typically includes the following:
- Terramycin Ophthalmic Ointment Indications
- Warnings and cautions for Terramycin Ophthalmic Ointment
- Direction and dosage information for Terramycin Ophthalmic Ointment
Terramycin Ophthalmic OintmentThis treatment applies to the following species:
with Polymyxin B Sulfate
Terramycin (oxytetracycline HCl) is an antibiotic, bright yellow in color, possessing potent antimicrobial activity. It is one of the most versatile of the broad-spectrum antibiotics, and is effective in the treatment of infections due to gram-positive and gram-negative bacteria, both aerobic and anaerobic, spirochetes, rickettsiae, and certain of the larger viruses.
Polymyxin B sulfate is one of a group of related antibiotics derived from Bacillus polymyxa. The polymyxins are rapidly bactericidal, this action being exclusively against gram-negative bacteria.
The broad-spectrum effectiveness of Terramycin against both gram-positive and gram-negative organisms is enhanced by the particular effectiveness of polymyxin B against infections associated with gram-negative organisms, especially those due to Pseudomonas aeruginosa, where polymyxin B is the antibiotic of choice. In addition, there is evidence to indicate that polymyxin B sulfate possesses some antifungal activity. The combined antibacterial effect of Terramycin plus polymyxin is at least additive and, in many instances, an actual synergistic action is obtained.
Terramycin Ophthalmic Ointment with Polymyxin B Sulfate is a suspension of oxytetracycline hydrochloride and polymyxin B sulfate in a special petrolatum base. Each gram of ointment contains oxytetracycline HCl equivalent to 5 mg of oxytetracycline and 10,000 units of polymyxin B as the sulfate.
Terramycin Ophthalmic Ointment Indications and UsageTerramycin Ophthalmic Ointment with Polymyxin B Sulfate is indicated for the prophylaxis and local treatment of superficial ocular infections due to oxytetracycline and polymyxin-sensitive organisms, including infections due to streptococci, rickettsiae, E. coli, and A. aerogenes, such as conjunctivitis, keratitis, pink eye, corneal ulcer, blepharitis in dogs, cats, cattle, sheep, and horses; ocular infections due to secondary bacterial complications of distemper in dogs, and bacterial inflammatory conditions which may occur secondary to other infectious diseases in the above species.
PrecautionsAllergic reactions may occasionally occur. Treatment should be discontinued if reactions are severe.
Note: The use of oxytetracycline and other antibiotics may result in an overgrowth of resistant organisms such as Monilia, staphylococci, and other species of bacteria. If new infections due to nonsensitive bacteria or fungi appear during therapy, appropriate measures should be taken.
Dosage and AdministrationTerramycin Ophthalmic Ointment with Polymyxin B Sulfate should be administered topically to the eye 2-4 times daily.
RECOMMENDED STORAGE: Store at controlled room temperature between 20° to 25°C (68° to 77°F), with excursions between 15° to 30°C (59° to 86°F).
How Supplied1/8-oz (3.5-g) tube
For Animal Use Only
Restricted Drug (California)-Use Only As Directed
Not for Human Use
NADA#8-763, Approved by FDA
Distributed by: Zoetis Inc., Kalamazoo, MI 49007
Made in Switzerland
Revised: June 2013
NAC No.: 3690179.3
333 PORTAGE STREET, KALAMAZOO, MI, 49007
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Copyright © 2015 North American Compendiums. Updated: 2014-12-03