Tenosynovitis Vaccine

This page contains information on Tenosynovitis Vaccine for veterinary use.
The information provided typically includes the following:
  • Tenosynovitis Vaccine Indications
  • Warnings and cautions for Tenosynovitis Vaccine
  • Direction and dosage information for Tenosynovitis Vaccine

Tenosynovitis Vaccine

This treatment applies to the following species:
Manufacturer: Merial Select

Tenosynovitis Vaccine, Modified Live Virus

U.S. Vet. Lic. No.: 279

Active Ingredient(s): The vaccine contains a live strain of tenosynovitis virus that has been modified by numerous passages through tissue cultures of chicken embryo origin.

Penicillin, streptomycin sulfate, and fungizone are added as bacteriostats and preservatives.

Notice: The vaccine meets the requirements of the U.S. Department of Agriculture in regards to safety, purity, potency and the capability to immunize normal, susceptible chickens.

Tenosynovitis Vaccine Indications

The vaccine is recommended for subcutaneous injection into healthy one day old chickens. The virus has been shown to aid in the prevention of tenosynovitis (viral arthritis) in young chickens.

Chickens to be vaccinated must be healthy and free of all diseases. It is essential that the birds be maintained under good environmental conditions, and that the exposure to disease viruses be reduced as much as possible in the field.

Dosage and Administration

Frozen Vaccine:

Preparation of Vaccine for Use: Important: Sterilize the vaccinating equipment by autoclaving for a minimum of 15 minutes at 121°C or by boiling in water for at least 20 minutes. Never allow chemical disinfectants to come into contact with the vaccinating equipment.

1. Add the contents of one (1) ampule to 1,600 mL of sterile diluent.

2. Remove only one (1) ampule of the vaccine at a time from the liquid nitrogen container and use immediately. Carefully observe all liquid nitrogen precautions, including wearing eye protection and gloves. Do not hold the ampule toward the face when removing it from a liquid nitrogen container. Never refreeze a vaccine ampule after thawing.

3. The contents of the ampule are thawed rapidly by immersing it in water at room temperature (15-25°C). Gently mix the ampule to disperse the contents. Break the ampule at its neck and quickly proceed as described below.

4. Remove the cover from the diluent container. Draw the contents of the ampule into a sterile 10 mL syringe fitted with an 18 or 20 gauge needle. Slowly add the contents of the vaccine ampule to the appropriate volume of diluent. Withdraw a small amount of the diluent, rinse the ampule once and add this to the vaccine-diluent mixture. Mix the contents of the bottle thoroughly by swirling and inverting the bottle. Do not shake.

Method of Vaccination: Give subcutaneously only.

1. Use a sterile automatic syringe with a 20-22 gauge, 3/8"-1/2" needle set to deliver 0.2 mL per dose. Check the accuracy of the delivery several times during the vaccination procedure.

2. Dilute the vaccine as directed, observing all precautions and warnings for handling.

3. Keep the bottle of diluted vaccine in an ice bath and agitate continuously.

4. Inject chickens under the loose skin at the back of the neck (subcutaneously). Hold the chicken by the back of the neck just below the head. The loose skin in this area is raised by gently pinching the thumb and forefinger. Insert the needle beneath the skin in a direction away from the head. Inject 0.2 mL per chicken. Avoid hitting the muscles and bones in the neck.

5. Use the entire contents of the container within one (1) hour after mixing.

Precaution(s): Ampules: Store in a liquid nitrogen container.

Diluent: Store at room temperature.

Liquid nitrogen container: Store in a cool, well-ventilated area. Check the liquid nitrogen level once a day. Keep the container away from incubator intakes and chicken boxes.

Liquid Nitrogen Precautions: The liquid nitrogen containers and vaccine should be handled by properly trained personnel only. These persons should be familiar with the Union Carbide Publication, “Precautions and Safe Practices - Liquefied Atmospheric Gases”, form #9888. Liquid nitrogen is extremely cold. Accidental contact with the skin or eyes can cause serious frostbite. Protect the eyes with goggles or a face shield, wear gloves and long sleeves when removing and handling frozen ampules, or when adding liquid nitrogen to the container. Storage and handling of liquid nitrogen containers should be in a well-ventilated area. Excessive amounts of nitrogen reduces the concentration of oxygen in the air of an unventilated space and can cause asphyxiation. If a person becomes drowsy or loses consciousness while working with liquid nitrogen, get the person to a well-ventilated area immediately. If breathing has stopped, apply artificial respiration and summon a physician immediately.

Caution(s): Use the entire contents when first opened.

Burn the container and all unused contents.

The ability of the vaccine to produce satisfactory results may depend on many factors, including, but not limited to, conditions of storage and handling by the user, administration of the vaccine, health and the responsiveness of individual chickens, and the degree of field exposure. Therefore, directions for use should be followed carefully.

The use of the vaccine is subject to applicable state and federal laws and regulations.

Warning(s): Do not vaccinate within 21 days before slaughter.

Presentation: 5 x 8,000 dose ampule of vaccine, with 1,600 mL of diluent.

NAC No.: 11050431

MERIAL, INC.
3239 SATELLITE BLVD., DULUTH, GA, 30096
Telephone:   888-637-4251
Website:   www.merial.com
Every effort has been made to ensure the accuracy of the Tenosynovitis Vaccine information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2014 North American Compendiums. Updated: 2014-07-28

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