Pyran 35 Tablets (Canada)

Manufacturer: Vétoquinol

DIN 02184567

Veterinary Use Only

Pyrantel Pamoate tablets

Description

: Pyran 35 (Pyrantel Pamoate) is an anthelmintic. It is a crystalline, water insoluble, tasteless salt of tetrahydropyrimidine base and pamoic acid with the name Trans-1,4,5,tetrahydro-1-methyl-2-(2-(2-thienyl)-vinyl)-pyrimidine hydrogen pamoate. Pyrantel Pamoate formula is C₁₁H₁₄N₂S.C₂₃H₁₆O₆ and its molecular weight is 594.686.

MODE OF ACTION: Pyran 35 has an anthelmintic effect by interfering with the neuro-muscular function of the parasite.

Composition

Pyran 35 is available as a small orange scored tablet containing Pyrantel Pamoate equivalent to 35 mg of Pyrantel base per tablet.

Pyran 35 Tablets Indications

Pyran 35 tablets are indicated for the treatment of the following parasite infestations in dogs, puppies and cats:

While Pyran 35 is not effective in removing whipworms (Trichuris vulpis) from dogs, treatment will result in a significant egg count reduction. Pyran 35 is ineffective in the control of tapeworms.

Contraindications

There are no known contraindications.

Pyran 35 Tablets Caution

The same precautions should be taken with Pyran as with other cholinesterase inhibitors.

Pharmacology

The anthelmintic activity of Pyran 35 has been demonstrated in several laboratory model infections utilizing mice, rats and dogs. These tests showed the compound to be effective for the control of hookworm and roundworm infestations. Pyran 35 is poorly absorbed by the intestinal mucosa so that its activity is confined to the lumen of the bowel. In the dog the peak plasma levels were low, and similarly the tissue levels were low. Less than 15% is excreted via the urine, the major proportion of the dose being excreted in the feces.

Pyran 35 Tablets Dosage And Administration

Cats

Administer orally at dose of 20 mg pyrantel base/kg of body weight (1 tablet per 1.75 kg B.W.).

Dogs And Puppies

Administer orally at dose of 5 mg pyrantel base/kg of body weight (1 tablet per 7 kg B.W.). For severe infestations in puppies, repeat in 7-10 days.

No fasting or purging is necessary prior to administration of the drug.

Warning

Keep out of reach of children.

Storage

Store in a dry place between 15 and 30 °C. Protect from exposure to light.

AVAILABILITY: Pyran 35 tablets come packaged in white, opaque HDPE bottle with permaseal cap, rayon coil stuffing, in sizes of 100 and 500 tablets.

Made in Canada

Vétoquinol N.-A. Inc., 2000, ch. Georges, Lavaltrie, QC, Canada J5T 3S5

NAC No.: 12341273