Pyran 125 Tablets (Canada)

This page contains information on Pyran 125 Tablets for veterinary use.
The information provided typically includes the following:
  • Pyran 125 Tablets Indications
  • Warnings and cautions for Pyran 125 Tablets
  • Direction and dosage information for Pyran 125 Tablets

Pyran 125 Tablets

This treatment applies to the following species:
Manufacturer: Vétoquinol

Veterinary Use Only

Pyrantel Pamoate tablets

DIN 02184605

Description

Pyran 125 (Pyrantel Pamoate) is an anthelmintic. It is a crystalline, water insoluble, tasteless salt of tetrahydropyrimidine base and pamoic acid with the name Trans-1,4,5,tetrahydro-1-methyl-2-(2-(2-thienyl)-vinyl)-pyrimidine hydrogen pamoate. Pyrantel Pamoate formula is C11H14N2S.C23H16O6 and its molecular weight is 594.686.

MODE OF ACTION: Pyran 125 has an anthelmintic effect by interfering with the neuro-muscular function of the parasite.

Composition

Pyran 125 is available as a small orange scored tablet containing Pyrantel Pamoate equivalent to 125 mg of Pyrantel base per tablet.

Pyran 125 Tablets Indications

Pyran 125 tablets are indicated for the treatment of parasite infestations in dogs, puppies and cats:

 

Cats

Dogs and Puppies

Roundworm

Toxocara cati

Toxocara canis

Toxascaris leonina

Hookworm

Ancylostoma spp

Ancylostoma caninum

Uncinaria stenocephala

While Pyran 125 is not effective in removing whipworms (Trichuris vulpis) from dogs, treatment will result in a significant egg count reduction. Pyran 125 is ineffective in the control of tapeworms.

Contraindications

There are no known contraindications.

Pyran 125 Tablets Caution

The same precautions should be taken with Pyran as with other cholinesterase inhibitors.

Pharmacology

The anthelmintic activity of Pyran 125 has been demonstrated in several laboratory model infections utilizing mice, rats and dogs. These tests showed the compound to be effective for the control of hookworm and roundworm infestations. Pyran 125 is poorly absorbed by the intestinal mucosa so that its activity is confined to the lumen of the bowel. In the dog the peak plasma levels were low, and similarly the tissue levels were low. Less than 15% is excreted via the urine, the major proportion of the dose being excreted in the feces.

Pyran 125 Tablets Dosage And Administration

Cats

Administer orally at dose of 20 mg pyrantel base/kg of body weight (1/2 tablet per 3 kg B.W.).

Dogs And Puppies

Administer orally at dose of 5 mg pyrantel base/kg of body weight (1 tablet per 25 kg B.W.). For severe infestations in puppies, repeat in 7-10 days.

No fasting or purging is necessary prior to the administration of the drug.

Warning

Keep out of reach of children.

Storage

Store in a dry place between 15°C and 25°C. Protect from exposure to light.

AVAILABILITY: Pyran 125 tablets come packaged in white, opaque HDPE bottle with permaseal cap, rayon coil stuffing, in sizes of 100 tablets.

Made in Canada

Vétoquinol N.-A. Inc., 2000, ch. Georges, Lavaltrie, QC, Canada J5T 3S5

Net

Code

 

100 tablets

20078

990950B

NAC No.: 12341285

VÉTOQUINOL N.-A. INC.
Commercial Division

2000, CHEMIN GEORGES, LAVALTRIE, QC, J5T 3S5
Telephone:   450-586-2252
Order Desk:   800-363-1700
Fax:   450-586-4649
Website:   www.vetoquinol.ca
Email:   info@vetoquinol.ca
Every effort has been made to ensure the accuracy of the Pyran 125 Tablets information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the Canadian product label or package insert.

Copyright © 2014 North American Compendiums. Updated: 2014-09-05

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