Pyramid IBR (Canada)

Bovine Rhinotracheitis Vaccine

Modified Live Virus

Veterinary Use Only

Pyramid IBR Indications

For vaccination of healthy cattle as an aid in the prevention of disease caused by bovine rhinotracheitis virus. This vaccine may be used in pregnant cows or calves nursing pregnant cows provided the cows were vaccinated pre-breeding, according to label instructions, with Pyramid FP 5, Pyramid FP 10, or Pyramid 2 + Type II BVD.

Composition

This product contains IBR modified live virus, with neomycin, polymyxin B, and thimerosal as preservatives.

Pyramid IBR Dosage And Administration

Aseptically rehydrate with the accompanying diluent. Shake well. Inject one 2 mL dose subcutaneously, using aseptic technique. Annual revaccination is recommended. Protect animals from exposure for at least 14 days after vaccination. Calves vaccinated under 6 months of age should be revaccinated at 6 months of age.

Summary Of Pregnant Cow Safety Study

Safety in pregnant cows and heifers was demonstrated in trials conducted in three separate herds of more than 1,400 cows. Prior to breeding, all animals were vaccinated with Pyramid FP 5, a modified live virus (MLV) vaccine containing IBR, BVD types 1 & 2, PI3, and BRSV. During the first, second or third trimester of pregnancy, the animals were vaccinated again. The pregnant cows received either Pyramid FP 5 or a killed virus (KV) IBR, BVD types 1 & 2, PI3, and BRSV vaccine (Triangle^® 4 + Type II BVD). From pregnancy vaccination through calving, the cows were observed for fetal loss. Fetal loss in both groups was similar with 0.9% in the Pyramid FP 5 vaccinated groups and 1.6% in the KV vaccinated groups. In addition, no abortions due to IBR or BVD were identified in either group. Following birth, each calf’s health was monitored for 30 days. The health of calves born to Pyramid FP 5 vaccinated dams was similar to the health of calves born to the KV vaccinated dams. Fetal health risks associated with vaccination of pregnant animals with modified live vaccines cannot be unequivocally determined by clinical trials conducted for licensure. Vaccination of pregnant animals with modified live vaccines should be discussed with a veterinarian.

Precautions

Store in dark at 2-7°C. Do not freeze. Use entire contents when first opened. A small percentage of animals may show transient mild injection site swelling. Do not vaccinate within 21 days before slaughter. Burn container and all unused contents. In case of anaphylactoid reaction, administer epinephrine.

Patent pending.

Pyramid^® is a registered trademark of Boehringer Ingelheim Vetmedica, Inc. Used under license.

Manufactured By: Boehringer Ingelheim Vetmedica, Inc., St. Joseph, Missouri 64506 U.s.a.

U.s. Vet. License No. 124

Manufactured For: Boehringer Ingelheim (canada) Ltd., Burlington, Ontario L7l 5h4

Nac No.